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| First name: || Melissa |
| Last name: || Duhaime |
| Country: || United States |
|Marine Phage Genomics
||Max Planck Institute for Marine Microbiology
International Max Planck Research School of Marine Microbiology (Marmic)
M.Sc. March 2007
Ph.D. expected 2009
B.A. in Biological Sciences
||Woods Hole Oceanographic Institute
Guest Student Fellow
Dr. Stefan Sievert, Dr. Stace Beaulieu, Dr. Tim Shank
Analysis of Tica Vent microbial mat diversity on the East Pacific Rise using
||Max Planck Institute - Bremen
Dr. Nicole Dubilier, Dr. Frank Oliver Glöckner
Metabolic characterization of Olavius algarvensis 5-symbiont consortia.
Annotation of symbiont BAC libraries.
||Monterey Bay Aquarium Research Institute
Dr. Robert Vrijenhoek, Dr. Joe Jones
Symbiont diversity of cold seep and hydrothermal vent vestimentifera; 16S and
Rubisco phylogenetics. Cruise to whale-fall for "Green snot worm."
|Scientific Interests and Goals:
|Viruses are the most abundant biological entity and largest source of genetic
material on the planet; marine environments contain on average 10^7
bacteriophage per liter of seawater. I will take two approaches to study marine
GENOMICS: Novel approaches are needed to grasp the impact of viruses on the
reservoir of genes directing the central metabolism of the world's oceans. The
potential for marine viruses to act as "gene shuttles" between species is well
known. Their impact on the gene pool of marine microbes has not been
extensively studied. The 20 marine phage genomes and 7+ metagenomes contain
tremendous unidentifiable diversity; this is the biggest obstacle in phage
genomics. My goal is to develop a structure sequence environment to finally mine
available marine virus datasets to ask intriguing biological questions.
POPULATION DYNAMICS: Virioplankton communities play a central role in the
dynamics of marine food webs. They are major predators of bacterioplankton and
significant sinks of essential nutrients, thus impacting global nutrient
cycling. Neither the community composition and spatial distribution of specific
virus communities, nor the link between virus-induced diversity and ecosystem
functioning are well known. I plan to use both community fingerprinting methods,
as well as virus "group specific markers" to qualitatively and quantitatively
assess changes in virus populations through time at Helogland (North Sea).
|Richter M, Lombardot T, Kostadinov I, Kottmann R, Duhaime MB, Peplies J,
Glockner FO. JCoast - A biologist-centric software tool for data mining and
comparison of prokaryotic (meta)genomes. BMC Bioinformatics. 2008 Apr; 9:177.
Vrijenhoek RC, Duhaime M, Jones WJ. Subtype variation among bacterial
endosymbionts of tubeworms (Annelida: Siboglinidae) from the Gulf of
Biol Bull. 2007 Jun; 212(3):180-4.